Ru-catalyzed hydrogenation of 3,5-diketo amides: simultaneous control of chemo- and enantioselectivity.
نویسندگان
چکیده
By modulating the chelating priorities of the different directing groups in 3,5-diketo amides with the assistance from coordinating solvent, highly chemo- and enantioselective hydrogenation of the C3-carbonyls was achieved in the presence of [RuCl(benzene)(S)-SunPhos]Cl in THF.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 71 شماره
صفحات -
تاریخ انتشار 2012